November 8               全天注册registration

November 9

8:00-11:30        Morning session (上午会议)

Moderators (主持人):

Dexi Chen(陈德喜), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

James Ou, University of Southern California, USA

8:00-8:15        Ni Li (李宁)

首都医科大学附属北京佑安医院院长，北京市肝病研究所所长

Opening Remarks

(开幕词）

The Frontier of Autophagy Research-1(自噬研究前沿-1)

8:15-9: 00        John Lemasters

University of South Carolina, USA

Mitophagy: types, initiators and role in mitochondrial quality control

(线粒体自噬: 类型, 启动机制, 及在线粒体质控中的作用)

Theme 1. Role of Autophagy in Hepatic Homeostasis

(主题1.自噬在肝脏稳态平衡中的作用)

9:05-9:50        Dexi Chen (陈德喜)

Capital Medical University, YouAnHospital, Beijing Institute of Hepatology(首都医科大学附属北京佑安医院，北京市肝病研究所)

Autophagy and the liver diseases

(自噬和肝脏疾病)

9:55-10:40        Wen-Xing Ding (丁文兴)

University of Kansas Medical Center, Kansas City, Kansas, USA

TFEB-mediated lysosome biogenesis in acute-on-chronic alcohol-induced liver injury

(酒精性肝炎中TFEB介导的溶酶体生成机制)

10:45-11:30        Wei An (安威)

首都医科大学基础医学院

Mitophagy and liver regeneration

(线粒体自噬与肝再生)

11:30-1:30        Lunch Break

1:30-5:00        Afternoon session (下午会议)

Moderators (主持人):

Xiao-Ming Yin (殷晓鸣), Indiana University School of Medicine

Feng Ren (任锋), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

The Frontier of Autophagy Research-2(自噬研究前沿-2)

1:30-2:15        Li Yu (俞立)

清华大学生命科学学院

Mechanism of autophagic lysosome reformation

(自噬性溶酶体再生之机理)

Theme 2. Role of Autophagy in Liver Tumorigenesis

(主题2.自噬在肝癌发生中的作用)

2:20-3:05        Masaaki Komatsu

Niigata University, Japan

Autophagy-specific substrates, p62 and NBR1 serve as drive gene products in hepatocellular carcinoma

(自噬特异性底物p62 和NBR1是肝细胞癌的驱动性基因产物)

3:10-3:55        Huiguo Ding (丁慧国)

Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

Hepatic stellar cells affect the autophagy of hepatocellular carcinoma cells by H2S and its molecular mechanism

(肝星状细胞通过H2S影响肝癌细胞自噬的分子机制)

4:00-4:45        James Ou

University of Southern California, USA

Autophagy and Hepatocarcinogenesis

(自噬和肝细胞癌的发生机制)

4:45-5:00        End of day discussion

November 10

8:00-11:30        Morning session (上午会议)

Moderators (主持人):

John Lemasters, University of South Carolina, USA

Huiguo Ding (丁慧国), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

The Frontier of Autophagy Research-3(自噬研究前沿-3)

8:15-9: 00        Eeva-LissaEskelina

University of Helsinki, Finland

Dissecting phagophore assembly site using 3D electron microscopy

(用3D电子显微镜术分析自噬膜前体形成的位置)

Theme 3. Role of Autophagy in Hepatic Viral Infection

(主题3.自噬在病毒性肝炎中的作用)

9:05-9:50        Zhengdong Zhao (赵振东)

中国医学科学院病原所

HCV and autophagy

(乙肝病毒和自噬)

9:55-10:40        Aleem Siddiqui 

University of California at San Diego, USA

Mitochondrial dynamics, mitophagy and innate immunity in viral hepatitis

(病毒性肝炎中线粒体动态，线粒体自噬和天然免疫的关系)

10:45-11:30        Ying Shi (石英)

Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

Apotentialstrategy to inhibit HBV replication through reducing hepatocytic autophagy

乙型肝炎病毒诱导的自噬及一种通过降低肝细胞自噬抑制HBV复制的新策略

11:30-1:30        LunchBreak

1:30-5:00        Afternoon session (下午会议)

Moderators (主持人):

Wen-Xing Ding (丁文兴), University of Kansas Medical Center, Kansas City, Kansas, USA

Ying Shi (石英), Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

The Frontier of Autophagy Research-4(自噬研究前沿-4)

1:30-2:15        Xiao-Ming Yin (殷晓鸣)

Indiana University School of Medicine, USA

The homeostatic role of autophagy in preventing liver injury

(自噬在预防肝损伤中的稳态作用)

Theme 4.  Role of Autophagy in Liver Injury 

(主题4.自噬在肝脏损伤中的作用)

2:20-3:05        Feng Ren (任锋)

Capital Medical University, YouAnHospital, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

The Critical role of autophagy in the pathogenesis of liver failure and its molecular regulatory mechanisms

(自噬在肝衰竭病理中的关键作用及分子调节机理)

3:10-3:55        Yu Li (李于)

中国科学院营养研究所

Finding a target for Berbering in the liver

(寻找小檗碱在肝脏中的靶点)

4:00-4:45        Xiuhui Li (李秀慧)

Capital Medical University, YouAnHostpical, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

Role of autophagy in the prevention and treatment of acute liver injury by Chinese Medicine

(自噬在中医药防治急性肝损伤中的作用)

4:50-5:00        DexiChen(陈德喜)

Capital Medical University, YouAnHostpical, Beijing Institute of Hepatology (首都医科大学附属北京佑安医院，北京市肝病研究所)

Closing Remarks

(闭幕词）