由冷泉港亚洲主办的2014年冷泉港亚洲会议：疾病模型和药物研发将于2014年8月25日-29日在苏州独墅湖会议酒店举行。

会议介绍：
We are pleased to announce Cold Spring Harbor Asia conference on Disease Modeling and Drug Discovery which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday August 25, and will conclude after lunch on August 29, 2014.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in disease modeling and drug discovery. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Recent developments in stem cell biology and cellular reprogramming have catalyzed unprecedented advances in disease modeling and drug discovery. The ability to derive distinct human cell types is enabling innovative approaches to create in vitro disease models and to develop new strategies for the identification and testing of novel therapeutics. The meeting will provide an opportunity to share new ideas and information about the generation of induced pluripotent stem cells (iPSCs), reprogramming in human oocytes using somatic cell nuclear transfer (SCNT), the derivation and analysis of diverse human cell types, and the development of disease-in-a-dish models as well as animal models. Additionally, there will be much focus on the use of these models for understanding disease mechanisms and discovering novel drugs for treating injury and diseases. Studies focused on neurodegenerative diseases, neurological and psychiatric disorders, cardiac diseases, diabetes and aging-related disorders will be among the highlighted topics for discussion. Leading scientists from around the globe will participate in discussions and provide penetrating insights towards a deeper understanding of human diseases and rationales for the development of more effective drugs and therapeutic solutions. 

会议主题：（Topics）
Cardiac disease modeling and drug discovery
Modeling psychiatric disorders using animal models
Modeling neurodevelopmental diseases using iPSCs
Dissecting neurodegenerative diseases using stem cells
Drug discovery using disease models
Cellular reprogramming
Clinical applications of disease models
Translating discovery to the clinics

Keynote Speakers:
Lorenz Studer, Sloan-Kettering Institute for Cancer Research, USA
Abstract title:TBA
Roberto Iacone, Hoffman-La Roche Ltd, Switzerland, SWITZERLAND 
Abstract title:Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human inducible pluripotent stem cells

Invited Speakers:
Anne G. Bang, Sanford-Burnham Medical Research Institute, USA
Abstract title:Human Induced Pluripotent Stem Cells and Patient Specific Cell-Based Disease Models for Drug Discovery
Thomas Bourgeron, Institut Pasteur, FRANCE
Abstract title:Genes, Synapses and Autisms
Arlene Chiu, Beckman Research Institute of City of Hope, USA
Abstract title: The Rocky Road from Discovery to Treatment
Ing-Ming Chiu, National Health Research Institutes, Taiwan, TAIWAN
Abstract title: Neural Stem Cells and Induced Neurons in Peripheral Nerve Injury Repair 
Alan Colman, Harvard University / Institute of Medical Biology, Singapore
Abstract title: The X Factor: Dynamics of X Chromosome Expression during and after Reprogramming of Human Somatic Cells 
Dieter Egli, The New York Stem Cell Foundation Research Institute, USA
Abstract title:Reprogramming in Human Ooyctes
Yadong Huang, University of California San Francisco, Gladstone Institute, USA
Abstract title: Modeling Neurodegenerative Diseases and Drug Screening Using Human iPSCs
Haruhisa Inoue, Kyoto University, JAPAN 
Abstract title:The Use of iPSCs toward the Treatment of Neurodegenerative Diseases
Juan Carlos Izpisua Belmonte, the Salk Institute, USA
Abstract title:Disease Models for Tissue and Organ Regeneration 
Dong-Wook Kim, Yonsei University College of Medicine, Korea
Abstract title: Modeling and Drug Discovery of X-linked Adrenoleukodystrophy using iPS Cells
Eric Klann, New York University, USA
Abstract title: Translating Translational Control in Brain Disorders 
Guo-Li Ming, Johns Hopkins University, USA
Abstract title: Modeling Complex Psychiatric Disorders Using iPSCs
Stephen Minger, GE Healthcare, UK
Abstract title: Innovating Preclinical Drug Discovery and Human Cell Therapy 
Lisa Monteggia, UT Southwestern Medical Center at Dallas, USA
Abstract title: Mechanism of Rapid Antidepressant Action 
Duanqing Pei, Chinese Academy of Sciences, CHINA
Abstract title:TBA 
Bruno Reversade, Institute of Medical Biology, A*STAR, SINGAPORE
Abstract title: Age-defying Proline, Because You Are Worth It 
Yanhong Shi, Beckman Research Institute of City of Hope, USA
Abstract title: Modeling Neurological Diseases using Patient iPSCs 
Toru Takumi, RIKEN Brain Science Institute, JAPAN
Abstract title: CNV Models for Autism Spectrum Disorders
Leslie Thompson, University of California Irvine, USA
Abstract title:Discovery and validation of therapeutic targets for Huntington's disease using HD iPS cells 
Joseph Wu, Standford University, USA
Abstract title: Cardiac Stem Cells for Modeling Heart Disease and for Drug Discovery
Michael Yaffe, California Institute for Regenerative Medicine, USA
Abstract title:Large-scale Derivation and Banking of iPSCs for Complex Human Diseases 
Su-chun Zhang, University of Wisconsin Madison, USA
Abstract title: Dissecting Early Pathogenesis in Neural Degeneration Using Human Stem Cells

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