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PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会

PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会

会议时间:2016-04-05 08:00:00至 2016-04-07 18:00:00结束
会议地点:上海 上海金茂君悦大酒店 浦东新区世纪大道88号
会议规模:暂无
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推荐参加:2017年微生物,病毒与免疫国际研讨会(CMVI 2017) (时间:2017-12-01 地点:三亚 )

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会议通知


第三届“PEGS China:蛋白与抗体工程与研发峰会”将于2016年代表4月5日至7日再次在上海召开。

经过一年的精心筹备和策划,此次峰会将提供更广泛的主题,更深切的探讨,并标榜多名来自中美欧等国的领英科学家。200多名行业领导者将聚集于此,在历时三天的峰会上分享案例研究、未发表的数据、开展的讨论、以及关于中国生物医药行业的发展趋势和未来的观点。

2016年会议日程包括:
•Protein&Antibody Engineering 蛋白与抗体研发工程会议   
将汇聚顶尖研究人员,分享他们对蛋白与抗体分子设计和优化的见解,讨论他们在克服挑战的过程中采用的前沿技术和创新方法。

•Analytical Characterization of Biotherapeutics 生物药物特性分析会议    
将展现生物结构与功能评估的尖端工具、技术和方法,确定物理化学性质以及分析新型生物制剂和生物仿制药的高阶结构。

•Next-Generation Cancer Biotherapeutics 新一代肿瘤生物治疗会议   
将呈现开发下一代生物偶联技术、双特性和多特性抗体的临床更新的战略、展示性能更强的新型工程抗体,以提升疗效和抗肿瘤活性,此外还将提出发展免疫疗法抗体过程中克服挑战的方案。

•Protein Aggregates &Stability 蛋白质聚集和稳定性会议    
将邀请科学家们讨论聚集机制、预测聚集倾向、进行稳定性研究并比较蛋白质聚集体和粒子的界定工具和量化工具。

•Symposium on Clinical and Regulatory Strategies for Domestic and Global IND and BLA Filing 生物制品临床与监管战略座谈会  
聚焦于中国与全球新药研究(IND)和生物制品许可申请(BLA)的机会和方法。座谈会将针对现今适用于国际开发新产品的评估战略方式进行深切探讨。

【参会对象】

生物医药公司的研发人员/ 研发助理/研发总监/ 科学家/ 项目总监/VP

会议名称:PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会

会议时间:2016年04月5-7 日

举办地点:上海.金茂君悦大酒店

美国CHI 主办方:美国CHI

介绍:美国CHI Scientific,Inc.自2004年创立以来就致力于打造原代细胞生物制药研发和筛选平台,联合了哈佛医学院,麻州医学院等27家顶级实验室科研力量,开发成功了 1050多种自主研发的高质量的原代细胞类产品并拥有原代细胞试剂盒领域的多项国外专利技术。目前已累积了3000多家优质客户,主要客户包括美国哈佛医 学院、斯坦福大学、耶鲁大学、哥伦比亚大学等知名大学附属医院和科研机构,并与美国国家生命科学研究院、美国国家癌症研究院以及辉瑞、默克、强生等20多家美国制药百强企业建立了良好的合作关系,产品畅销欧美市场。

会议日程


会议日程:

•Protein&Antibody Engineering 蛋白与抗体研发工程会议   
将汇聚顶尖研究人员,分享他们对蛋白与抗体分子设计和优化的见解,讨论他们在克服挑战的过程中采用的前沿技术和创新方法。

•Analytical Characterization of Biotherapeutics 生物药物特性分析会议    
将展现生物结构与功能评估的尖端工具、技术和方法,确定物理化学性质以及分析新型生物制剂和生物仿制药的高阶结构。

•Next-Generation Cancer Biotherapeutics 新一代肿瘤生物治疗会议   
将呈现开发下一代生物偶联技术、双特性和多特性抗体的临床更新的战略、展示性能更强的新型工程抗体,以提升疗效和抗肿瘤活性,此外还将提出发展免疫疗法抗体过程中克服挑战的方案。

•Protein Aggregates &Stability 蛋白质聚集和稳定性会议    
将邀请科学家们讨论聚集机制、预测聚集倾向、进行稳定性研究并比较蛋白质聚集体和粒子的界定工具和量化工具。

•Symposium on Clinical and Regulatory Strategies for Domestic and Global IND and BLA Filing 生物制品临床与监管战略座谈会  
聚焦于中国与全球新药研究(IND)和生物制品许可申请(BLA)的机会和方法。座谈会将针对现今适用于国际开发新产品的评估战略方式进行深切探讨。

注:详细日程请下载(右边干货分享位置)PDF文档《PEGS2016蛋白抗体研发峰会中文会议日程》

会议嘉宾


PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会

Weikang Tao
Jiangsu Henrui Medicine Co., Ltd. Ph.D., Vice President & CEO, R&D Center
演讲主题:Cancer Immunotherapy: Delivering the Promise——癌症免疫疗法:承诺的实现

Recent breakthroughs in treating different types of advanced-stage malignancies by harnessing self immunity against neoplastic cells showed a great promise of immunotherapy for cancer treatment. Various strategies have been employed to unleash, enhance or elicit anticancer immune reactions, which include T-cell checkpoint blockade, engineered T cells, BiTE, modified cytokines and cancer vaccines. This presentation will review recent progress in cancer immunotherapy and discuss some immunotherapeutic agents discovered and developed at HengRui Medicine Co., Ltd.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Daotian Fu
Livzon MabPharm Ph.D., General Manager

演讲主题:Update on Recent Regulatory Changes for Biologics Development in China——中国生物制剂研发的最新监管变

Over the past several years, the biotech industry in China has experienced tremendous growth, both in biosimilars and innovative biologics. In the meantime, the CFDA is also going through significant reforms with respect to guidance and the reviewing process for development of both biosimilars as well as innovative biologics. In this presentation, the author intends to provide an update on the recent development in CFDA’s guidance for biologics development in China, and how the biotech industry can best position itself to take advantage of the recent regulatory changes.

PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会 
Herren Wu
MedImmune/AstraZeneca Ph.D., CTO
演讲主题:Engineering the Next-Generation Antibody-Drug Conjugates for Cancer Therapy——用于癌症治疗的新一代抗体偶联药物

Linking of highly potent cytotoxic warheads to tumor-targeting antibodies has the potential to attack tumors with missile-like precision and avoid toxicity to normal tissues. However, clinical observations indicate that the therapeutic window of most antibody-drug conjugates (ADCs) remains narrow. I will discuss our efforts in developing next-generation ADC technology which seeks to address the short-comings observed with current ADCs and help realize the full potential of this drug class to provide new breakthrough agents for the treatment of cancer.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Andrew Bradbury
Biosciences Division, Los Alamos National Laboratory MBBS, Ph.D., Research Scientist and Group Leader
演讲主题: AT THE CROSSROADS:GETTING TO REPRODUCIBLE RESEARCH ANTIBODIES——站在十字路口:如何获得可重复研究的抗体

Researchers all over the world routinely use antibodies, a critical class of commercially supplied reagents that are frequently unreliable. This situation affects reproducibility in biomedical research, wastes millions of dollars annually, and may affect clinical trials. This talk will provide an overview of the problem, argue that the time has come to express antibodies recombinantly and refer to them by their sequences, and provide possible ways to get to this ideal.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Paul W.H.I. Parren
Senior Vice President & Scientific Director, Genmab Ph.D.,
演讲主题:Developing Antibody-Drug Conjugates for the Treatment of Solid Cancers——抗体偶联药物治疗实体肿瘤的进展

Therapeutic antibodies have revolutionized the treatment of cancer. However, many patients still fail to respond or become resistant to targeted treatment and novel innovative approaches to improve therapy are therefore required. Chemical engineering of antibodies, fueled by recent molecular insights, is providing important opportunities for the development of more potent antibody therapeutics. The progress in two antibodydrug conjugate programs from Genmab’s portfolio will be highlighted.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Alain Beck
Antibody and ADC Physico-Chemistry, Centre d’Immunologie Pierre Fabre, France Ph.D., Senior Director,
演讲主题:KEYNOTE PRESENTATION: CUTTING-EDGE MASS SPECTROMETRY METHODS FOR ANTIBODY,BIOSIMILAR, BISPECIFIC AND ANTIBODY-DRUG CONJUGATES STRUCTURAL ASSESSMENT——抗体的尖端质谱法,双特异性生物仿制和抗体药物共轭结构的评估

A plethora of new mass spectrometry (MS) methods are used for antibody structural characterization and for biosimilarity assessment. In addition, these techniques are used to design and optimize more sophisticated and potent antibody derivatives such as ADCs (OptimADCs), bi- and multispecific antibodies, and controlled mixture of antibodies. Case studies based on state-of-the art MS methods such as Native and Ion-Mobility MS, Top-Down Sequencing, Proteomics and Sheathless Capillary Electrophoresis−Tandem MS will be presented and discussed.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Peter M.Tessier
Rensselaer Polytechnic Institute Ph.D., Richard Baruch M.D. Career Development Asso
演讲主题:Improved Methods for Designing and Evolving Antibodies——抗体设计和进化的改良方法

The biotech industry has seen an explosion in the development of therapeutic antibodies in the last decade. The advantages of antibodies are
compelling. Nevertheless, there are many challenges associated with antibody selection and engineering that require key technical advances to
simplify the rapid and reliable generation of potent antibody therapeutics. I will discuss.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Roland Kontermann
Institute of Cell Biology and Immunology, University of Stuttgart Ph.D., Professor, Biomedical Engineering
演讲主题:Engineering Principles to Generate Multivalent Antibody-TRAIL Fusion Proteins——多价抗体-TRAIL融合蛋白的制造工程原则

Fusion of TRAIL to antibody fragments has been shown to allow for a targeted delivery and the selective induction of tumor cell death.
We have engineered optimized single-chain derivatives of TRAIL (scTRAIL), which were employed to develop novel multivalent antibody-scTRAIL
fusion proteins with improved properties. These multivalent fusion proteins were generated employing either scFv-driven homodimerization or
various separate homodimerization modules. Targeting and controlled dimerization of scTRAIL fusion proteins provides a strategy to enforce
apoptosis induction, together with retained tumor selectivity and good in vivo tolerance.

 PEGS China 2016 第三届中国蛋白与抗体工程及研发峰会
Salvador Ventura
Biochemistry and Molecular Biology, Institute of Biotechnology and Biomedicine, University of Barcelona Ph.D., Professor
演讲主题:DESIGNING PROTEIN SOLUBILITY——设计蛋

One of the major challenges that one should face during the development of protein-based biopharmaceuticals is their inherent propensity to aggregate. Indeed, protein therapeutic agents are both stored and typically administered at very high concentrations. Under these conditions they can easily aggregate, impacting the product’s developability, stability, formulation, and immunogenicity. I will discuss how computationally-assisted design of protein structures solubility is helping us to overcome these limitations.

会议门票


PEGS China 2016

标准套餐  (包括两个会议和SEMINAR)                                           
Early Registration Rates until January 15                                6360.00
Advance Registration Rates until February 26                         6890.00
Standard Registration Rates after February 26 and onsite       7420.00

 

基础套餐  (包括一个会议或者SEMINAR )                                       
Early Registration Rates until January 15                                4770.00
Advance Registration Rates until February 26                        5300.00
Standard Registration Rates after February 26 and onsite      5830.00

*以上价格均为含税价, 提供正式发票.

上海金茂君悦大酒店 会议场地:上海金茂君悦大酒店

交通指南:[机场]上海虹桥机场: 距25公里 [机场]上海浦东国际机场: 距40公里 [市中心]人民广场: 距4公里 [火车站]上海火车站: 距7.5公里

介绍:上海金茂君悦大酒店位于88层金茂大厦的53-87层,曾被2000年吉尼斯世界纪录千禧年版评为“世界最高酒店”。拥有548间豪华客房的上海金茂君悦大酒店地处浦东高速发展的商业金融区陆家嘴的中心,离上海国际会议中心仅五分钟,距豫园和外滩——上海著名的邻江大道、以及大道旁耸立的古典风格建筑群只有十分钟路程。从酒店到虹桥国际机场只需四十分钟,到浦东国际机场只需四十五分钟。金茂大厦坐落于浦东金融中心的核心位置,周围众多A级办公楼。靠近上海新国际博览中心和世博公园。金茂君悦酒店是上海家喻户晓的一家高品质5星级酒店。金茂大厦共88层,酒店有548间客房,提供的服务和设施业内首屈一指,其客房风格典雅大方,有各类宴会设施,餐饮场所及健身中心,距离各主要商业中心及旅游景点交通便捷。酒店的548间客房及套房,位于金茂大厦的58至85层,有13种不同房型。56层开始是宏伟的镂空中庭设计。全新装修的客房已开始接受预订。客房入口全部精巧的选择了角度,最大限度保证客房的私密与安全。全新升级的房间选择了简洁时尚的内部装饰,色彩明快,色调温馨,特别为酒店手工订制的地毯图案,写意地呈现出中国汉字“回”,似乎寓意着“回家”,令人感受到如归家般的温馨亲切。

标签: 肿瘤 抗体 疫苗 生物治疗

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